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Nexium is a brand name of Esomeprazole drug. It provides a reduction of the stomach secretion and inhibiting action in the role of the proton pump. The active components added into the drug are meant to reduce the activity of the proton pumps and in high therapeutic concentrations it completely blocks them. This favors the lowering of basal and stimulating excretion of the hydrochloric acid in the stomach.
The use of this drug first of all gets rid the patient of such symptoms as heartburn, difficult swallowing, cough, painful sensations in the stomach, sleep disorder, and vomiting. This drug may be used in the purposes of the prophylaxis of ulcers of the stomach and even caner of the stomach. And it may be also used in combination with antibiotics to treat some types of the intestinal ulcers caused by the bacterial infection.Nexium starts acting almost at once after the use. It provides a direct pharmacological action to the proton pump which stimulates secretion of the gastric juice as a result of which there is a reduction of the concentration of the hydrochloric acid in the stomach. Even during the consumption of the meals when the proton pump is especially stimulated for the production of the hydrochloric acid Nexium helps to control its function. The pharmacological effect is developed within 4 weeks after the beginning of the use.
The food consumption slows down and at the same time reduces the absorption of Nexium in the stomach, however it does not provide a significant influence on the effect of the drug as to the endogastric acidity. Therefore the drug may be used both with meals and before meals. Each tablet should be taken with plenty of water.
Some side effects which are possible during the use of Nexium are conditioned by the pharmacological action of the drug. Oftentimes, the side effects appear from the side of the gastro-intestinal tract: stomachache, diarrhea, flatulency, nausea, vomiting, and constipations.
Only in some cases the patient may experience headache or allergic reaction. These side effects tell that the patient has the increased sensitivity to the drug components and maybe in this case the medication has to be replaced.
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